15 Most Horrifying Rare Diseases. From terrifying rare diseases caused by nasty parasites to scary psychological illnesses that can kill you, here are 15 of the worst and most horrifying rare diseases and disorders that you don’t want to have.

This list of the most horrifying rare diseases in the world includes:

Elephantiasis,
Trimethylaminuria (Fish Odor Syndrome),
Guinea Worm Disease (Dracunculiasis),
Filarial Worm,
Cancrum Oris (Noma),
Blaschko’s Lines,
Fecal Vomiting,
Cornu Cutaneum,
Eumycetoma (Madura Foot),
Pica,
Necrotizing Fasciitis,
Polyglandular Addison’s Disease,
Fibrodysplasia Ossificans Progressiva,
Harlequin Ichthyosis,
Fatal Familial Insomnia.

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Infections from tickborne diseases in the US are steadily increasing — and new tickborne diseases have been discovered in recent years. Ticks are vectors that can carry infectious agents such as bacteria, viruses, or parasites. When an infected tick bites a person or an animal, the tick’s saliva transmits infectious agents that can cause illness. Some ticks can transmit multiple diseases. These “co-infections” pose challenges for diagnosing, treating and preventing tickborne diseases.

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